Plasmodium vivax Merozoite surface protein 8 is a highly immunogenic protein that localizes to the food vacuole of the malaria parasite
作者单位:Department of Parasitology Wuxi Medical School Jiangnan University Department of Medical Environmental Biology and Tropical Medicine School of Medicine Kangwon National University Chuncheon Mahidol Vivax Research Unit Faculty of Tropical Medicine Mahidol University Division of Malaria Research Proteo-Science Center Ehime University
会议名称:《第十一届全国免疫学学术大会》
会议日期:2016年
关 键 词:Plasmodium vivax malaria MSP8 food vacuole Immunity
摘 要:Plasmodium vivax merozoite surface protein 8(Pv MSP8)contains GPI motif and double EGF-like domains,which are considered potential targets of protective immunity.In our previous screening,recombinant Pv MSP8(r Pv MSP8)has been highly detected for recognizing with vivax-infected patient sera.However,the vaccine potential of Pv MSP8 needs adequately evaluated.In present study,purified r Pv MSP8 protein possessed potent antigenicity