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Preparation and in vitro release behaviour of Urapidil Hydro...

Preparation and in vitro release behaviour of Urapidil Hydrochloride Loading into microspheres based on PLLA

作     者:Hao Hong~(1*) Zhao Tao Guan Xiaoyu School of Chemical Engineering Northwest University Xi’an 710069 

会议名称:《The 5th Joint China/Japan Chemical Engineering Symposium》

会议日期:2009年

学科分类:08[工学] 0805[工学-材料科学与工程(可授工学、理学学位)] 080502[工学-材料学] 

关 键 词:urapidil hydrochloride poly(L-lactide)(PLLA) microsphere loading efficiency 

摘      要:正Poly(L-lactide)(PLLA) microspheres were prepared using different *** surface morphology and the size of the microspheres were observed by ***,the drug loading efficiency of microspheres and the in vitro release of urapidil hydrochloride from microspheres were *** urapidil hydrochloride-PLLA microspheres exhibited better sustained-release capacity.

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