Population-Based and Personalized Design of Total Knee Replacement Prosthesis for Additive Manufacturing Based on Chinese Anthropometric Data
作者机构：Department of Orthcpaedics and TraumatologyFaculty of MdicineThe Chinese University of Hong KongHong Kong 999077China Genter for Transiational Medicine Resarch and Developmentherzhet Institues of Advaned TechnologyChinese Academy of ScenesShenzhen 518055China Department of Orthopedirs and Traumatology Nanjing Drum Tower HospitalThe Affiliated HospitalNanjing University Medial SchoolNanjing 210008China Institute for BiomechanicsBerufgenos senschaftliche Unfallklinik MurnauMurnanu am Staffelsee 82418Cermany Instinute for BiomechanicParacelsus Medical University SazburgSatzburg 5020Austria
出 版 物：《Engineering》 (工程（英文）)
年 卷 期：2021年第7卷第3期
页 面：386-394页
核心收录：
学科分类：08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）]
基 金：supported by the Shandong Weigao Orthopedic Device Co. Ltd. (the company was not involved in data analysis)
主 题：Additive manufacturing Population-based design Total knee replacement Knee prosthesis Anthropometric measurement
摘 要：At present,most total knee replacement(TKR)prostheses on the market are designed according to the sizes of ***,extensive studies have indicated that human anatomies differ among different ethnicities.A number of reports have indicated that Chinese TKR patients do not match with available *** this study,computed tomography(CT)images of 52 knees of Chinese men and women were used for anthropometric *** and geometric measurements were definedand used for correlation *** parameters from the measurement results were *** geometries of knees were measured as coordinates.A deformable three-dimensional(3D)knee modelbased on anatomical coordinates correlating with the identified key parameters was generated.A pros-thesis was then designed according to the analyzed *** matching analysis,bone resectionanalysis,and cadaveric trials were conducted and compared with commercial products to validate theproposed *** femoral component designed by this study resulted in the highest accuracy(rootmean square point-to-surface(RMS PS),(1.08±0.20)mm)and lowest amount of resected bone volume(27412mm^(3))in comparison with two commercial knee *** study suggests a new approachfor population-based patient-specific femoral prosthesis design With a single,easilty acquired dimen-sion-namely,epicondyle width(ECW)-as input,a patient-specific femoral prosthesis can be designed according to the analyzed measured data and manufactured by additive manufacturing(AM)***,the reconstructed femoral condylar surface was compared with the femoral condylar surfacein the original CT scanning data The average RMS PS distance of the reconstructed femoral condylar surface among all data was(1.10±0.18)mm,which is comparable to other statistical shape modeling methods using multiple radiographs as input *** is a need to develop an anthropometric-based knee prosthesis for the Chinese *** on
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