Antibacterial activity of leaves extracts of Trifolium alexandrinum Linn,against pathogenic bacteria causing tropical diseases

作     者：Abdul Viqar Khan Qamar Uddin Ahmed Indu Shukla Athar Ali Khan 

作者机构：Department of BotanyFaculty of Life SciencesAligarh Muslim University Department of Pharmaceutical ChemistryFaculty of PharmacyInternational Islamic University Malaysia Department of MicrobiologyJawaharlal Nehru Medical CollegeAligarh Muslim University 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2012年第2卷第3期

页      面：189-194页

学科分类：1008[医学-中药学(可授医学、理学学位)] 0710[理学-生物学] 071001[理学-植物学] 1006[医学-中西医结合] 07[理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：financially supported by SERC Fast Track OYSSchem Department of Science and Technology(DST) New Delhi India[grant No.304/2004(SR/FT/L-129/2004)] 

主　　题：Trifolium alexandrinum L. Fabaceae Antibacterial activity Pathogenic bacteria Gram-positive bacteria Gram-negative bacteria Tropical disease Infectious disease 

摘      要：Objective:To investigate antibacterial potential of Trifolium alexandrinum(***) Linn,against seven gram positive and eleven gram negative hospital isolated human pathogenic bacterial strains responsible for many tropical ***:Non-polar and polar extracts of the leaves of *** i.e.,hexane,dichloromethane(DCM),ethyl acetate(EtOAc), methanol(MeOH) and aqueous(AQ) extracts at five different concentrations(1,2,5,10 and 15 mg/ mL) were prepared to evaluate their antibacterial *** standards were strictly followed to perform antimicrobial disc susceptibility test using disc diffusion ***:Polar extracts demonstrated significant antibacterial activity against tested *** and MeOH extracts showed maximum antibacterial activity with higher inhibition zone and were found effective against seventeen of the tested *** AQ plant extract inhibited the growth of sixteen of the test *** and MeOH plant extracts inhibited the growth of all seven gram positive and ten of the gram negative bacterial ***:The present study strongly confirms the effectiveness of crude leaves extracts against tested human pathogenic bacterial strains causing several tropical *** Egyptian clover is used as a fodder plant,it could be helpful in controlling various infectious diseases associated with cattle as well.