Current understanding of multi-species biofilms

作     者：Liang Yang Yang Liu Hong Wu Niels Hoiby Soren Molin Zhi-jun Song 

作者机构：Department of Systems Biology Technical University of Denmark Lyngby DK-2800 Denmark Department of Clinical Microbiology Rigshospitalet Copenhagen N DK-2100 Denmark 

出 版 物：《International Journal of Oral Science》 (国际口腔科学杂志（英文版）)

年 卷 期：2011年第3卷第2期

页      面：74-81页

核心收录：

学科分类：0710[理学-生物学] 0821[工学-纺织科学与工程] 071010[理学-生物化学与分子生物学] 07[理学] 08[工学] 082104[工学-服装设计与工程] 

主　　题：biofilms extracellular polymeric substances structure development interactions 

摘      要：Direct observation of a wide range of natural microorganisms has revealed the fact that the majority of microbes persist as surface-attached communities surrounded by matrix materials, called biofilms. Biofilms can be formed by a single bacterial strain. However, most natural biofilms are actually formed by multiple bacterial species. Conventional methods for bacterial cleaning, such as applications of antibiotics and/or disinfectants are often ineffective for biofilm populations due to their special physiology and physical matrix barrier. It has been estimated that billions of dollars are spent every year worldwide to deal with damage to equipment, contamina- tions of products, energy losses, and infections in human beings resulted from microbial biofilms. Microorganisms compete, cooperate, and communicate with each other in multi-species biofilms. Understanding the mechanisms of multi-species hiofilm formation will facilitate the development of methods for combating bacterial hiofilms in clinical, environmental, industrial, and agricultural areas. The most recent advances in the understanding of multi-species biofilms are summarized and discussed in the review.