Comparison of Serum Phospholipase A<sub>2</sub>Activities of All Known Extant Crocodylian Species

作     者：Mark Merchant Charles McAdon Stephanie Mead Justin McFatter Caleb D. McMahan Rebeckah Griffith Christopher M. Murray 

作者机构：Department of Chemistry McNeese State University Lake Charles LA USA The Field Museum of Natural History Chicago IL USA Department of Math Computer Science and Statistics McNeese State University Lake Charles LA USA Department of Biology Tennessee Technological University Cookeville TN USA 

出 版 物：《Advances in Biological Chemistry》 (生物化学进展（英文）)

年 卷 期：2017年第7卷第4期

页      面：151-160页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Antibacterial Antimicrobial Crocodilian Crocodylia Crocodylidae Gavialidae Innate Immunity Phylogeny PLA2 

摘      要：Serum samples from all 23 extant crocodilian species were tested for phospholipase A2 (PLA2) activity against nine different bacterial species. The data were used?to generate a PLA2 activity profile for each crocodilian species, and the data were used to compare the activities of the three main lineages (Alligatoridae,?Crocodylidae, and Gavialidae), the seven different genera, and to compare all?of the 23 individual species. The data revealed that the three lineages ofcrocodilians (Alligatoridae, Crocodylidae, and Gavialidae) exhibited PLA2 activities toward nine species of bacteria that were statistically?distinguishable. In?addition,?the PLA2 activities of crocodilians in a specific genus tended to be more similar to other?members in their genus than to members of other crocodilian genera.