Interferon-induced progression of autoimmune thyroiditis with enlarged thyroid glands in gynecological patient: A case report and literature review
Interferon-induced progression of autoimmune thyroiditis with enlarged thyroid glands in gynecological patient: A case report and literature review作者机构：Division of Experimental Endoscopic Surgery Imaging Technology and Minimally Invasive Therapy Department of Obstetrics and Gynecology Vito Fazzi Hospital Lecce Italy Moscow State University of Medicine & Dentistry Named after A. I. Evdokimov Moscow Russia National Medical Academy of Post-Graduate Education Named after P. L. Shupik Ministry of Health of Ukraine Kyiv Ukraine Peoples’ Friendship University of Russia Moscow Russia The Institute of Reproductive Technologies AltraVita Moscow Russia Xatzikosta General Hospital Ioannina Greece
出 版 物：《Open Journal of Obstetrics and Gynecology》 (妇产科期刊（英文）)
年 卷 期：2013年第3卷第2期
页 面：257-261页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Autoimmune Thyroiditis Human Papillomavirus Interferon Thyroid Glands
摘 要：A case report presents a progression of autoimmune thyroiditis with an abnormal enlargement of the thyroid glands and increased thyreotropin hormone concentration-associated with interferon treatment in human papillomavirus infected patient with the autoimmune thyroiditis and a daily L-thyroxin hormone replacement therapy background. Observation was supplemented with a brief review of literature and discussion. On the basis of this observation and a brief review of literature authors suggested that the potential adverse effects of interferon therapy are overbalanced than its benefits for gynecological patients, therefore any interferon treatment should be recommended with strict indications as well as after screening of conditions and functions of thyroid glands and other interferon target organs to avoid interferon treatment side effects. Practitioners especially gynecologists should inform their patients about pleiotropic interferon effects and its high frequent and wide range side effects before to start such kind of treatment.
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