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Syringoceles of Cowper’s ducts and glands in adult men

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Asian Journal of Andrology 2020年第2期22卷 129-133页

作者： Simon Bugeja Anastasia Frost Stella Ivaz Mariya Dragova Daniela E Andrich Anthony R Mundy Reconstructive Urology Unit University College London Hospitals NHS Foundation TrustLondon NW12PGUK

Cowper’s syringoceles are uncommon,usually described in children and most commonly limited to the *** describe more complex variants in an adult population affecting with varying degrees of severity,the glands themselves,and the complications they may lead *** hundred consecutive urethrograms of patients with unreconstructed strictures were ***-six patients(mean age:41.1 years)with Cowper’s syringoceles who were managed between 2009 and 2016 were subsequently ***,radiological appearance,treatment(when indicated),and outcomes were *** 100 urethrograms in patients with strictures,33.0%demonstrated filling of Cowper’s ducts or glands,occurring predominantly in patients with bulbar *** 1 of 26 patients with non-bulbar strictures had a visible duct/*** 26 symptomatic patients,15 presented with poor *** four patients,a grossly dilated Cowper’s duct obstructed the *** the remaining 11 patients,a bulbar stricture caused the symptoms and the syringocele was identified *** patients presented with perineal *** six of them,fluoroscopy and magnetic resonance imaging(MRI)revealed complex multicystic lesions within the bulbourethral *** patients developed perineoscrotal *** the 11 patients with strictures,the syringocele was no longer visible after *** three of four patients with urethral obstruction secondary to a dilated Cowper’s duct,this resolved after transperineal excision(n=2)and endoscopic deroofing(n=1).Five of six patients with complex syringoceles involving Cowper’s glands were excised surgically with symptomatic relief in *** conclusion,Cowper’s syringocele in adults is more common than previously thought and may cause lower urinary tract symptoms or be associated with serious complications which usually require surgical treatment.

关键词： complications Cowper’s glands syringocele treatment urethral stricture

Morphological and cytological changes of meibomian glands in patients with type 2 diabetes mellitus

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International Journal of Ophthalmology(English edition) 2019年第9期12卷 1415-1419页

作者： Tao Yu Xu-Guang Han Yang Gao Ai-Ping Song Guang-Fu Dang Shandong Provincial Qianfoshan Hospital the First Hospital Affiliated with Shandong First Medical UniversityJinan 250014Shandong ProvinceChina Jinan Aier Ophthalmology Hospital Aier Eye Hospital GroupJinan 250014Shandong ProvinceChina2Jinan

AIM: To observe the changes of microcellular structure of meibomian glands(MGs) in type 2 diabetes mellitus(DM), and to explore its correlation with the duration of ***: The study assessed 132 eyes of 132 patients with type 2 diabetes mellitus(DM group) and 100 eyes of 100 non-diabetic participants(NDM group). All patients underwent the examination of the Keratograph 5 M system to obtain the meibography which were used to evaluate the structure dropout of the MGs. And then laser scanning confocal microscopy(LSCM) was performed for observing the acinar cells and ducts of the MGs to obtain the following parameters: the MG acinar unit density(MGAUD), MG acinar longest diameter(MGALD) and MG acinar shortest diameter(MGASD). The examination results of the right eye were selected for ***: Compared with that in NDM group, the meiboscore was significantly higher(Z=-4.057, P<0.001), and there were more MGs dropout in DM group. With the prolongation of the course of diabetes, the absence of MGs aggravated and the MGs dropout score increased(r=0.596;P<0.001). LSCM showed that there were various cytological alterations in acinar cells of MGs with the progress of diabetes duration, such as expansion, atrophy or fibrosis of MG acinar units, decreased density of MG acinar units, deposition of lipid substances, infiltration of inflammatory cells, proliferation of fibrous tissues, etc. And the opening of the glandular duct changed from smooth at the beginning to narrow, blocked, fibrotic and so on. Compared with that in NDM group, the MGAUD in DM group was significantly lower(Z=-9.713;P<0.001), the MGALD and MGASD were significantly larger(Z=-9.751,-6.416;P<0.001). With the duration of diabetes, the MGAUD reduced, the MGASD increased(r=0.860, 0.364, P<0.001);but the MGALD had no correlation with diabetic duration(r=0.133, P=0.151).CONCLUSION: With the progress of diabetes, the meibomian glandular acinar cells of diabetic patients show various manifestations

关键词： diabetes meibomian glands tear films keratograph laser scanning confocal microscopy

Participation of peribiliary glands in biliary tract pathophysiologies

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World Journal of Hepatology 2013年第8期5卷 425-432页

作者： Saya Igarashi Yasunori Sato Xiang Shan Ren Kenichi Harada Motoko Sasaki Yasuni Nakanuma Department of Human Pathology Kanazawa University Graduate School of Medicine

AIM:To investigate the roles of peribiliary glands around the bile ducts in the pathophysiology of the biliary ***:The expression of fetal pancreatic markers,pancreatic duodenal homeobox factor 1(PDX1)and hairy and enhancer of split 1(HES1)and endodermal stem/progenitor(S/P)cell markers[CD44s,chemokine receptor type 4(CXCR4),SOX9 and epithelial cell adhesion molecule(EpCAM)]were examined immunohistochemically in 32 normal adult livers(autopsy livers)and 22 hepatolithiatic livers(surgically resected livers).The latter was characterized by the proliferation of the peribiliary *** was performed using formalin-fixed,paraffin-embedded tissue sections after *** PDX1and HES1 were expressed in both the nucleus and cytoplasm of epithelial cells,only nuclear staining was ***9 was expressed in the nucleus,while CD44s,CXCR4 and EpCAM were expressed in the cell *** frequency and extent of the expression of these molecules in the lining epithelia and peribiliary glands were evaluated semi-quantitatively based on the percentage of positive cells:0,1+(focal),2+(moderate)and 3+(extensive).RESULTS:In normal livers,PDX1 was infrequently expressed in the lining epithelia,but was frequently expressed in the peribiliary *** contrast,HES1was frequently expressed in the lining epithelia,but its expression in the peribiliary glands was focal,suggesting that the peribiliary glands retain the potential of differentiation toward the pancreas and the lining epithelia exhibit properties to inhibit such *** unique combination was also seen in hepatolithiatic *** expression of endodermal S/P cell markers varied in the peribiliary glands in normal livers:SOX9 and EpCAM were frequently expressed,CD44s infrequently,and CXCR4 almost not at *** expression of these markers,particularly CD44s and CXCR4,increased in the peribiliary glands and lining epithelia in hepatolithiatic *** increa

关键词： Biliary tree Peribiliary glands Pancreatic duodenal homeobox factor 1 Stem cells Differentiation Pancreas

Alleviating effects of melatonin on oxidative changes in the testes and pituitary glands evoked by subacute chlorpyrifos administration in Wistar rats

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Asian Pacific Journal of Tropical Biomedicine 2012年第8期2卷 645-650页

作者： Angela J Umosen Suleiman F Ambali Joseph O Ayo Bisala Mohammed Chidiebere Uchendu Department of Veterinary Pharmacology Ahmadu Bello University Department of Veterinary Physiology Ahmadu Bello University Department of Veterinary Pathology Ahmadu Bello University

Objective:To evaluate the alleviating effects of melatonin on oxidative changes in the testes and pituitary gland induced by subacute chlopyrifos（CPF） exposure in ***:Forty adult male Wistar rats divided into 4 groups of 10 animals were used for the *** I received soya oil（2 mL/kg） while group II was administered with melatonin（0.5 mg/kg）.Group III was administered CPF only(8.5 mg/kg l/10th of the LD50) while group Ⅳ was pretreated with melatonin（0.5 mg/kg） and then exposed to CPF（8.5 mg/kg）,10 min *** regimens were administered by gavage once daily for a period of 28 *** the end of the exposure period, the rats were sacrificed and the testicular tissues and pituitary glands were evaluated for the malonaldehyde（MDA） concentration and activities of superoxide dismutase（SOD） and catalase（CAT）.Results:CPF increased MDA concentrations and reduced the activities of SOD and CAT in the testes and pituitary *** pretreatment reduced the testicular and pituitary MDA concentrations and improves the SOD and CAT ***:the study showed that subacute CPF-induced oxidative stress in the testes and pituitary glands were alleviated by melatonin due to its antioxidant property.

关键词： Chlorpyrifos Oxidative stress Testes Pituitary glands Alleviation Melatonin

Phytochemical and anti-bacterial activity of epidermal glands extract of Christella parasitica (L.) H. Lev.

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Asian Pacific Journal of Tropical Biomedicine 2011年第1期1卷 8-11页

作者： Paul Raj K Irudayaraj V Johnson M Patric Raja D Dartment of Plant Biology and Plant Biotechnology St.Xavier's College(Autonomous)

Objective:To study the morphology,biochemistry and bioactivity of the epidermal glands of the glandular morphotype of Christella parasitica(***)(L.) ***: Morphological studies on epidermal glands were earned out by using light microscope and scanning electron *** prepare the extract,the shade-dried fronds of glandular morphotype were soaked in *** antibacterial studies paper disc method was followed by using various pathogenic ***:Detailed micromorphological,phytochemical and bioactivity studies on a medicinal fern ***(L.) *** its inlraspecific variation in antibacterial *** presence or absence of the epidermal glands was the key factor for antibacterial activity in the morphovariants of this *** epidermal glands were orange-coloured,stalked and elongated ones of about 84.2μm×45μm,and distributed on the undersurface of cosla,coslules and veins in croziers,young and mature *** of glands varied from 15/cm on costa in mature leaves to 140/cm on costules in *** acetone extract of the glands showed antibacterial activities and also toxic effect against mosquito larvae and tadpoles of *** phytochemical analysis and HPLC studies of the gland extract showed the presence of various kinds of terpenoids,alkaloids,tannins,saponins and flavonoids in ***:The present study shows that epidermal glands of the glandular morphotype of C. parasitica(L.) *** several bioactive compounds and such rare moiphovariant should be conserved in *** next step is to isolate the pure compounds and to screen the bioactivity of individual compounds of the epidermal glands.

关键词： Epidermal glands Christella parasitica Bioactivity Phytochemical activity Anti-bacterial activity Morphology Biochemistry Glandular morphotype Light microscope Shade-dried frond Bioactive compound Morphovariant Preliminary phytochemical analysis Gland extract Flavonoid

The Ultrastructural Changes of Adult Porcine Thyroid glands Following TSH Stimulation in Organ Culture

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中国医科大学学报 1991年第S2期20卷 21-23页

作者：洪生明朱继江张丽红 Department of Pathology China Medical University. Shenyang China

A culture technique had been developed by which the normal mor-phological integrity of the porcine thyroid tissue was well preserved. Few ultra-strvctural changes following TSE stimulation could be detected compared withthe control group. Parafollicular cells were detected after being cultured for 96h in the presence of TSH. For the first time, we used scanning electron micro-scope to study the ultrastructural changes of organ cultured thyroid gland.

关键词： organ culture thyroid glands TSH

Interferon-induced progression of autoimmune thyroiditis with enlarged thyroid glands in gynecological patient: A case report and literature review

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Open Journal of Obstetrics and Gynecology 2013年第2期3卷 257-261页

作者： Ospan Mynbaev Marina Eliseeva Artem Chernov Ioannis Kosmas Andrea Tinelli Victor Radzinsky Victor Tsarev Division of Experimental Endoscopic Surgery Imaging Technology and Minimally Invasive Therapy Department of Obstetrics and Gynecology Vito Fazzi Hospital Lecce Italy Moscow State University of Medicine & Dentistry Named after A. I. Evdokimov Moscow Russia National Medical Academy of Post-Graduate Education Named after P. L. Shupik Ministry of Health of Ukraine Kyiv Ukraine Peoples’ Friendship University of Russia Moscow Russia The Institute of Reproductive Technologies AltraVita Moscow Russia Xatzikosta General Hospital Ioannina Greece

A case report presents a progression of autoimmune thyroiditis with an abnormal enlargement of the thyroid glands and increased thyreotropin hormone concentration-associated with interferon treatment in human papillomavirus infected patient with the autoimmune thyroiditis and a daily L-thyroxin hormone replacement therapy background. Observation was supplemented with a brief review of literature and discussion. On the basis of this observation and a brief review of literature authors suggested that the potential adverse effects of interferon therapy are overbalanced than its benefits for gynecological patients, therefore any interferon treatment should be recommended with strict indications as well as after screening of conditions and functions of thyroid glands and other interferon target organs to avoid interferon treatment side effects. Practitioners especially gynecologists should inform their patients about pleiotropic interferon effects and its high frequent and wide range side effects before to start such kind of treatment.

关键词： Autoimmune Thyroiditis Human Papillomavirus Interferon Thyroid glands

Tumours of salivary glands in the stomatology and maxillo-facial surgery unit at the university hospital centre —Yalgado Ouédraogo

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Open Journal of Stomatology 2013年第9期3卷 465-470页

作者： Mathieu Millogo Tarcissus Konsem Haréfétéguén Bissa Rasmané Béogo Dieudonné Ouédraogo Service of Stomatology and Maxillo-Facial Surgery of the University Hospital of Tokoin Lomé Togo Service of Stomatology and Maxillo-Facial Surgery of the University Hospital Souro SANOU Bobo-Dioulasso Burkina Faso Service of Stomatology and Maxillo-Facial Surgery of the University Hospital Yalgado Ouédraogo Ouagadougou Burkina Faso

The aim of this study was to contribute to strengthening the efficiency in the treatment of the salivary gland tumours in the Stomatology and Maxillo-facial surgery service at the University Hospital Centre/Yalgado OUEDRAOGO of Ouagadougou. It has been a retrospective and descriptive study covering seven (7) years [January 2006-December 2012] on epidemiology and the treatment of 54 cases of the salivary glands tumours histologically confirmed. Benign tumours (non-malignant tumours were prevalent (61.11% of cases). The annual incidences were 4.71 cases for non malignant tumours and 3 cases for malignant tumours. The average age was 34-45 years for non malignant tumours and 44-33 years for malignant ones. In both groups, the tumour was discovered lately with an average 32-48 months before consulting in case of non malignant tumours and 18-29 months for malignant tumours. The location of non malignant tumours was very often the parotid (42.42%), under mandible gland (27.28%). Malignant tumours very often concerned the parotid (76.18%) and the under mandible gland (14.29%). The histology has revealed that pleomorphic adenoma was the leading type of non-malignant tumours (93.94% of cases) whereas carcinoma was predominant in malignant tumours (80.95% of cases). Long term track keeping was difficult and it has been complicated by the loss of contact with some patients. The low living standard, the time wasted before consulting, limited human resources and therapeutic means constitute handicaps to the treatment in our African context.

关键词： Tumours Salivary glands Epidemiology Histology Treatment

ELECTROACUPUNCTURE TREATMENT OF 30 CASES OF HYPERPLASIA OF MAMMARY glands

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World Journal of Acupuncture-Moxibustion 1995年第4期5卷 22-24页

作者：刘丽军李炎高郭诚杰

In the present paper,30 cases of hyperplasia of mammary glands were treated withelectroacupuncture in different times following menstruation,showing satisfactory *** totaleffective rate was up to 96.67％.In addition,t... 详细信息

关键词： Hyperplasia of mammary glands Electroacupuncture therapy