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Anthrax:an update

Anthrax:an update

作     者:Kamal SM Rashid AKM M Bakar MA Aliad MA 

作者机构:Department of MedicineKhulna Medical College Department of PaediatricsKhulna Medical College Department of Gastroenterologykhulna Medical College 

出 版 物:《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志(英文版))

年 卷 期:2011年第1卷第6期

页      面:496-501页

学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主  题:Anthrax Bacillus anthracis Zoonotic disease Contagious disease Cutaneous anthrax Inhalational anthrax Gastrointestinal anthrax Human anthrax 

摘      要:Anthrax is a zoonotic disease caused by Bacillus *** is potentially fatal and highly contagious *** arc the natural *** acquire the disease incidentally by contact with infected animal or animal *** the 18th century an epidemic destroyed approximately half of the sheep in *** 1900 human inhalational anthrax occured sporadically in the United *** 1979 an outbreak of human anthrax occured in Sverdlovsk of Soviet *** continued to represent a world wide *** incidence of the disease has decreased in developed countries as a result of vaccination and improved industrial *** anthrax clinically presents in three forms,***,gastrointestinal and *** 95%of human anthrax is cutaneous and 5%is *** anthrax is very rare(less than 1%).Inhalational form is used as a biological warefare agent. Penicillin,ciprofloxacin(and other quinolones),doxicyclin,ampicillin,***, clarithromycin,vancomycin,chloramphenicol,rifampicin are effective antimicrobials. Antimicrobial therapy for 60 days is *** anthrax vaccine is available. Administration of anti-protective antigen(PA) antibody in combination with ciprofloxacin produced 90%-100%*** combination of CPG-adjuvanted anthrax vaccine adsorbed(AVA) plus dalbavancin significantly improved survival.

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