Dendrobium orchid polysaccharide extract: Preparation,characterization and in vivo skin hydrating efficacy

作     者：Mayuree Kanlayavattanakul Tamonpatch Pawakongbun Nattaya Lourith 

作者机构：School of Cosmetic ScienceMae Fah Luang UniversityChiang Rai 57100Thailand Phytocosmetics and Cosmeceuticals Research GroupMae Fah Luang UniversityChiang Rai 57100Thailand 

出 版 物：《Chinese Herbal Medicines》 (中草药（英文版）)

年 卷 期：2019年第11卷第4期

页      面：400-405页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Mae Fah Luang University is acknowledged upon financial and facilities supports during this manuscript preparation 

主　　题：clinical study moisturizer orchid phytopharmaceuticals polysaccharide skin hydrating 

摘      要：Objective:Dendrobium spp.,the major globally commercializing tropical orchid,has been continuously used in Chinese ***,preparation and standardization of this therapeutic orchid including its clinical evidence for topical application are sparely to be ***:Maceration of the white orchid(Dendrobium *** Sanan)in water was varied on the extraction *** extraction yields and total polysaccharide content of the extracts were *** best extract condition was selected,standardized,and evaluated on safety and skin hydrating efficacy in human ***:The extraction for 3 h gave the extract with polysaccharide content that significantly(P0.001)greater than the other extraction times with the following specification:yield[(35.60±2.51)%],moisture content[(7.65±0.21)%],total polysaccharide,sugar,reducing sugar and ash content[(72.95±2.37)%,(34.38±0.00)%,(16.28±0.00)%,and(0.12±0.00)%],p H(4.42±0.01),viscosity[(15.07±0.12)cps]swelling and water absorption capacities[(10.00±0.00)%,(1.19±0.24)g/g].This antioxidative polysaccharide caused no skin irritation with a better skin hydrating efficacy than the untreated skin and the benchmark as examined in 22 Thai ***:White Dendrobium is ready to be supplied as a specialty ingredient with a safe and efficient profile for skin dryness *** innovative application of the identified traditional Chinese medicinal herb flows in the main stream of the consumers’preferences and demand upon natural derived products.