Dietary habits, lifestyle factors and neurodegenerative diseases

作     者：Aurel Popa-Wagner Dinu Iuliu Dumitrascu Bogdan Capitanescu Eugen Bogdan Petcu Roxana Surugiu Wen-Hui Fang Danut-Adrian Dumbrava Aurel Popa-Wagner;Dinu Iuliu Dumitrascu;Bogdan Capitanescu;Eugen Bogdan Petcu;Roxana Surugiu;Wen-Hui Fang;Danut-Adrian Dumbrava

作者机构：Griffith University School of MedicineGold Coast CampusQLDAustralia Department of AnatomyUMF“Iuliu Hatieganu”Cluj-NapocaRomania Department of Human AnatomyFaculty of MedicineUniversity of Medicine and PharmacyCraiovaRomania Center of Clinical and Experimental MedicineUniversity of Medicine and PharmacyCraiovaRomania School of Healthcare ScienceFaculty of Science and EngineeringManchester Metropolitan UniversityManchesterUK 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2020年第15卷第3期

页      面：394-400页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

主　　题：brain injury dietary habits lifestyle metaflammation neurodegeneration oxidative stress type 2 diabetes mellitus 

摘      要：Worldwide stroke is increasing in parallel with modernization,changes in lifestyle,and the growing elderly population.Our review is focused on the link between diet,as part of‘modern lifestyle’,and health in the context of genetic predisposition of individuals to‘unhealthy’metabolic pathway activity.It is concluded that lifestyle including high sugar diets,alcohol and tobacco addiction or high fat diets as well as ageing,brain injury,oxidative stress and neuroinflammation,negatively influence the onset,severity and duration of neurodegenerative diseases.Fortunately,there are several healthy dietary components such as polyunsaturated fatty acids and the anti-oxidants curcumin,resveratrol,blueberry polyphenols,sulphoraphane,salvionic acid as well as caloric restriction and physical activity,which may counteract ageing and associated neurodegenerative diseases via increased autophagy or increased neurogenesis in the adult brain.