Tandem Approach to Functionalized Pyrrolo[3,4-α]carbazole-1,3-diones via a Pd-catalyzed Indole-to-carbazole Transformation

作     者：GUO Lianghua XU Mei JIAN Yong LIU Sheng PAN Weidong DUAN Lian 

作者机构：State Key Laboratory of Functions and Applications of Medicinal PlantsGuizhou Medical UniversityGuiyang 550014P. R.China 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2019年第35卷第4期

页      面：621-626页

核心收录：

学科分类：08[工学] 081201[工学-计算机系统结构] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

基　　金：Supported by the National Natural Science Foundation of China(No.21762014) the Science Foundation of Guizhou Province, China(No. 2107) 

主　　题：Carbazole One-pot Tandem reaction Three-component reaction Indole-to-carbazole 

摘      要：A one-pot and efficient tliree-component reaction of indoles, acrylates and maleimides for the synthesis of pyrrolo[3,4-α]carbazole-1,3-dione derivatives was developed. Three C-C bonds and one ring were created in a single step via an indole-to-carbazole transformation triggered by Pd(II)-catalyzed direct C3-alkenylation of indoles.