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Pancreatic transplantation: Brief review of the current evidence

Pancreatic transplantation: Brief review of the current evidence

作     者:Ahmed Aref Tariq Zayan Ravi Pararajasingam Ajay Sharma Ahmed Halawa 

作者机构:Department of NephrologySur HospitalSur 411Oman Faculty of Health and ScienceInstitute of Learning and TeachingUniversity of LiverpoolLiverpool L69 3GBUnited Kingdom Department of TransplantationSheffield Teaching HospitalsSheffield S5 7AUUnited Kingdom Renal MedicineRoyal Liverpool University HospitalsLiverpool L7 8XPUnited Kingdom Department of Transplantation SurgerySheffield Teaching HospitalsSheffield S5 7AUUnited Kingdom 

出 版 物:《World Journal of Transplantation》 (世界移植杂志)

年 卷 期:2019年第9卷第4期

页      面:81-93页

学科分类:10[医学] 

主  题:Combined kidney pancrease transplantation Renal transplantation Diabetic kidney disease Diabetes mellitus 

摘      要:Kidney transplantation is the treatment of choice for management of end-stage renal ***,in diabetic patients,the underlying metabolic disturbance will persist and even may get worse after isolated kidney *** transplantation in humans was first introduced in *** initial outcome was ***,this was changed after the improvement of surgical techniques together with better patient selection and the availability of potent and better-tolerated immune-suppression like cyclosporine and induction *** kidney and pancreas transplantation will not only solve the problem of organ failure,but it will also stabilise or even reverse the metabolic complications of *** kidney and pancreas transplantation have the best long term outcome in diabetic cases with renal ***,at the cost of an initial increase in morbidity and risk of *** transplantation options include pancreas after kidney transplantation and islet cell *** aim by this work to explore various options which can be offered to a diabetic patient with advanced chronic kidney *** work will provide a simplified,yet up-to-date information regarding the different management options for those diabetic chronic kidney failure patients.

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