RE-DEVELOPMENT OF SYNAPTIC CONNECTIONS AFTER IMPLANTED SINGLE 5-HT CONTAINING NEURON IN ISOLATED LEECH GANGLIA

作     者：张人骥 ZHANG REN-JI (Department of Biology, Peking University)

作者机构：Department of Biology Peking University 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：1989年第32卷第1期

页      面：88-95页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：Project supported by the National Natural Science Foundation of China 

主　　题：leech synaptie re-development plasticity implanted neuron synapse forming. 

摘      要：Single mature Retzius cells which contain 5-HT have been implanted in isolated ganglia of Whitmania pigra. The properties of the implanted Retzius cell and its connections with the original identified nerve cells of the ganglia have been measured by intracellular microelectrodes. At 3 days in culture an implanted Retzius cell maintains its normal electrical membrane properties. It also forms the non-rectifying electronic coupling with the original Retzius cell and rectifying junctions with the L motor neuron of the host ganglion. In addition it receives chemical inputs of the impulse from T and N sensory neurons of ganglion. Impulses in the implanted Retzius cell evoke synaptic potentials in the L motor neuron, In this paper the appearance of novel synapses, which are formed by implanting an extra mature neuron as a pre- or post-synaptic element, is described. It might represent functional development of central nervous system at an earlier stage.