Green spermatozoa illuminate a 30-year-old model： sperm-egg adhesion involves intra-acrosomal proteins

作     者：Steve Tardif 

作者机构：Reproductive and Developmental Biology Group Centrefor Oncology and Molecular Medicine Division ofMedical Sciences Ninewells Hospital University ofDundee Dundee Scotland DD1 9SY UK 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2011年第13卷第5期

页      面：665-666页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 0905[农学-畜牧学] 08[工学] 0817[工学-化学工程与技术] 09[农学] 090501[农学-动物遗传育种与繁殖] 

主　　题：Green reexamination 

摘      要：Fertilisation in mammals involves many synchronized steps including spermegg adhesion. Prior to sperm-oolemma fusion, spermatozoa need to undergo the acrosome reaction （AR） or exocytosis. The universal belief, for many years, has been that the AR was initiated upon binding to the zona pellucida （ZP）. As such acrosomal proteins were not thought to be involved in the primary contact with the ZP. These proteins were only suggested to be biologically relevant once the sperm were attached to the ZP and during subsequent events. However,