Eosinopenia is a predictive factor for the severity of acute ischemic stroke

作     者：Hui-Min Zhao Wen-Qian Qin Pei-Ji Wang Zhong-Min Wen 

作者机构：Department of Neurologythe Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Department of Orthopedicsthe Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2019年第14卷第10期

页      面：1772-1779页

核心收录：

学科分类：0710[理学-生物学] 100208[医学-临床检验诊断学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学] 

主　　题：nerve regeneration eosinopenia eosinophil ischemia stroke infarct volume infection clinical outcome neutrophilia risk factors predictive factor neural regeneration 

摘      要：Previous data have revealed an association between eosinopenia and mortality of acute ischemic stroke.However,the relationship of eosinopenia with infarct volume,infection rate,and poor outcome of acute ischemic stroke is still unknown.The retrospective study included 421 patients(273 males,65%;mean age,68.0± 13.0 years)with first acute ischemic stroke who were hospitalized in the Second Affiliated Hospital of Soochow University,China,from January 2017 to February 2018.Laboratory data,neuroimaging results,and modified Rankin Scale scores were collected.Patients were divided into four groups according to their eosinophil percentage level(3)after adjusting for potential confounding factors(P-trend0.001).These findings suggest that eosinopenia has the potential to predict the severity of acute ischemic stroke.This study was approved by the Ethics Committee of the Second Affiliated Hospital of Soochow University,China(approval number:K10)on November 10,2015.