Mg-based absorbable membrane for guided bone regeneration(GBR): a pilot study

作     者：Wei Peng Jun-Xiu Chen Xian-Feng Shan Yi-Chuan Wang Fan He Xue-Jin Wang Li-Li Tan Ke Yang 

作者机构：Department of StomatologyAffiliated Zhongshan Hospital of Dalian UniversityDalian 116001China Medical School of Dalian UniversityDalian 116622China Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and EngineeringUniversity of Science and Technology of ChinaShenyang 110016China 

出 版 物：《Rare Metals》 (稀有金属（英文版）)

年 卷 期：2019年第38卷第6期

页      面：577-587页

核心收录：

学科分类：07[理学] 070205[理学-凝聚态物理] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0702[理学-物理学] 

基　　金：financially supported by the Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement (Nos.2016YFC1101804 and 2016YFC1100604) Shenyang Key R&D and Technology Transfer Program (No.Z18-0-027) 

主　　题：Bone defect Guided bone regeneration Ca–P-coated magnesium(Mg) membrane Bioabsorbable membrane 

摘      要：A novel calcium-phosphate(Ca–P)-coated magnesium(Mg) membrane used for guided bone regeneration(GBR) was *** microstructural characterization, electrochemical test, immersion test,fluorescence labeling analysis and histopathological evaluation were carried *** results showed that Ca–P coating could obviously improve the corrosion resistance of the pure Mg *** in vivo results showed that Mg membrane coated with Ca–P would take 8 weeks to be completely ***, Mg membrane was completely absorbed within 1 *** evaluation showed that the Ca–P-coated Mg membranes were significantly better than Ti membranes at the early implantation time(4 weeks), and with the time prolonging,the performance of the coated Mg membrane was not as good as pure Ti membranes(but still better than blank group) at 8 and 12 *** coated biodegradable Mg membrane had a good promising application in *** further studies have to be done to further decrease the degradation rate of pure Mg membrane.