Optimal use of fielder XT guidewire enhances the success rate of chronic total occlusion percutaneous coronary intervention
Optimal use of fielder XT guidewire enhances the success rate of chronic total occlusion percutaneous coronary intervention作者机构：Department of Cardiology State Key Laboratory of Organ Failure Research Nanfang Hospital Southern Medical University Department of CardiologyGeneral Hospital of Northern Theater Command
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2019年第7卷第8期
页 面：928-939页
核心收录：
学科分类：10[医学]
基 金：Supported by the National Natural Science Foundation of China,No.81570464 and No.81770271 Special Fund for the Cultivation of College Students’ Science and Technology Innovation in 2018,No.pdjha0095 Municipal Planning Projects of Scientific Technology of Guangzhou,No.201804020083
主 题：Chronic total occlusion Percutaneous coronary intervention Anterograde wire escalation Parallel wire technique Fielder XT guidewire Success rate
摘 要：BACKGROUND Chronic total occlusion(CTO) is found in 18-31% of patients who undergo coronary angiography. Successful recanalization of CTOs is associated with reduced recurrent angina pectoris rates and increased long-term *** the success rate of CTO percutaneous coronary intervention(CTO-PCI)has improved, CTO-PCI remains technically challenging. The Fielder XT guidewire was designed for CTO lesions. To validate whether the use of the guidewire increases the success rate, we compared the results of CTO-PCI with or without the guidewire. We hypothesized that the use of Fielder XT guidewire can increase the success rate of *** To investigate whether the use of Fielder XT guidewire increases the final procedural success of CTO-PCI via the anterograde *** Between January 2013 and December 2015, a retrospective study was conducted on 1230 consecutive patients with CTO who received PCI via the anterograde approach at the General Hospital of Northern Theater Command. The patients were divided into an XT Group(n = 686) and a no-XT Group(n = 544) depending on whether Fielder XT guidewire was used. Both groups were compared for clinical parameters, lesion-related characteristics, procedural outcomes and inhospital complications. The data were statistically analyzed using Pearson s χ~2 test for categorical variables, and Students t test was used to compare the quantitative data. Significant independent factors and a risk ratio with 95%confidence interval(CI) were assessed by multivariate logistic regression *** In total, 1230 patients were recruited; 75.4% of the patients were male, and 55.8%of the patients were in the XT group. The overall success rate was 83.9%, with87.8% in the XT group. Based on multivariate logistic regression analysis, factors positively associated with procedural success were the use of Fielder XT guidewire(P = 0.005, 95%CI: 1.172-2.380) and systolic blood pressure(P = 0.011,95%CI: 1.003-1.022), while fact
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