Hidden correlation of the effect mechanism on chronic gastritis treated with ginger-isolated moxibustion at different single acupoints

作     者：Jun-wei GU Xuming YANG Qi LI Muen GU Meng-die WU Shu-fei CAO Jing LI 顾俊薇;杨旭明;李琪;顾沐恩;吴梦蝶;曹淑菲;李璟

作者机构：Shanghai Yueyang hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai 200437China Shanghai University of Traditional Chinese MedicineShanghai 201023China Clinic of Laochenghuangmiao Tonghaichuntang ClinicShanghai 200010China 

出 版 物：《World Journal of Acupuncture-Moxibustion》 (世界针灸杂志（英文版）)

年 卷 期：2019年第29卷第1期

页      面：48-54页

核心收录：

学科分类：1005[医学-中医学] 100512[医学-针灸推拿学] 10[医学] 

基　　金：Supported by National Natural Science Foundation of China:81674071 Shanghai TCM technological innovation program:ZYKC201601002 

主　　题：Isolated ginger moxibustion Chronic gastritis Data mining Association algorithm 

摘      要：Objective: To observe the differences in the effects and mechanisms on chronic gastritis treated by ginger-isolated moxibustion at Zúsānlǐ(足三里ST 36) and Nèiguān(内关PC 6).Methods: A total of 60 eligible patients of chronic gastritis were randomized into two groups, a ST 36 group(ginger-isolated moxibustion at ST 36, 30 cases) and a PC 6 group(ginger-isolated moxibustion at PC 6, 30 cases). Before and after 6 treatments, the total variability of heart rate(TV) and the scores in Scale for gastrointestinal diseases of traditional Chinese medicine were determined and recorded. Using correlation analysis, the hidden correlation condition that affects the therapeutic outcomes was excavated from the data. With least square method, the gradient curve(K value) of TV in treatment was estimated and the correlation between the effect mechanism and autonomic nerve regulation was ***: ① In ST 36 group, the duration of sickness, severity of disease and the activity of autonomic nerve before treatment presented the underlying correlation with the therapeutic effects. In contrast, the hidden correlation in PC 6 group was not clear. ② In ST 36 group, the higher K value of TV in treatment was, the more significant the therapeutic effects were, but in PC group, K value was reversely related to the therapeutic ***: The therapeutic effects of ginger-isolated moxibustion at single acupoint are correlated with the duration and severity of sickness. The therapeutic effects in ST 36 group were improved by the modulation of autonomic nerve activity and the effects in PC 6 group were negatively correlated with autonomic nerve activity. It is deduced that the effect mechanisms are different on single acupoint for chronic gastritis between the two points.