青斑样血管病变:高压氧疗后的长期随访结果

作     者：Lee J.C. 王琼 

作者机构：DepartmentofDermatologyChangGungMemorialHospital199TunHwaNorthRoadTaipeiTaiwan 

出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)

年 卷 期：2006年第2卷第6期

页      面：20-21页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 1010[医学-医学技术（可授医学、理学学位）] 100215[医学-康复医学与理疗学] 10[医学] 

主　　题：青斑样血管病变 高压氧(HBO) 随访结果 高压氧疗 治疗困难 白色萎缩 反复发作 长期疗效 皮肤溃疡 恢复行走 

摘      要：Background: Livedoid vasculopathy, also known as atrophie blanche, is a recurrent painful vasculopathy appearing mostly on the lower limbs. Treatment is challenging and relapses are frequent. Objectives: To analyse the long-term effect and safety of hyperbaric oxygen (HBO) therapy in treating livedoid vasculopathy. Methods: Twelve patients with active livedoid vasculopathy were included in this study. All patients underwent HBO therapy five times a week. Each week photographs were taken and the total dose of analgesics was recorded. Side effects were documented and assessed. Recurrence was defined as the presence of skin ulceration. Results: Of the eight patients who completed the treatment, resumption of ambulation and reduction of analgesics were achieved at an average of 4.9 HBO therapy sessions. Leg ulcers in all eight patients healed completely at a mean of 3.4 weeks (range 2-5 weeks). Six patients suffered relapses of ulceration and responded to additional HBO therapy. No significant side-effects were found. Conclusions: HBO is a relatively safe, fast and effective method to treat patients with livedoid vasculopathy.