Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume
Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume作者机构：Post Graduate and Research Department of ZoologyVoorhees CollegePhysiology Wing
出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)
年 卷 期：2011年第1卷第5期
页 面：381-385页
学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学]
主 题：Hepatoprotective Ethanol Antioxidant enzymes Enicostemma littorale Blume Oxidative stress Hypolipidaemic effect
摘 要：Objective:To investigate the hypolipidaemic and antioxidant effects of aqueous leaf extract of Enicoslemma littorale(***)Blume(Ens)against ethanol induced hepatic injury in albino ***:Male albino rats of six numbers in each group were undertaken for *** and antioxidant effect of *** Blume(Ens)aqueous leaf extract at a dosage of 250 mg/kg bw was ***:Levels of serum and tissue cholesterol,triglycerides and free fatty acids were elevated and levels of tissue thiobarbituric acid reactive substances(TBARS)and lipid hydroperoxide were increased in ethanol treated *** activity levels of liver antioxidant enzymes such as superoxide dismutase(SOD),catalase(CAT),glutathione peroxidase(GPX)and glutathione-s-transferase(GST)were *** adiminstration of extract of E,littorale Blume,levels of cholesterol,triglycerides and free fatty acids were decreased in serum and liver tissue,levels of TBARS and lipid hydroperoxide were decreased,and Ever antioxidant enzymes were increased in liver tissue;Conclusions:It can be concluded that the aqueous leaf extract of E,littorale Blume(Ens)has potent restorative effect on hyperlipidaemic and oxidative stress.
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