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On the similarity/dissimilarity of DNA sequences based on 4D graphical representation

On the similarity/dissimilarity of DNA sequences based on 4D graphical representation

作     者:TANG XiaoChan ZHOU PanPan QIU WenYuan 

作者机构:Department of Chemistry State Key Laboratory of Applied Organic Chemistry Lanzhou University Lanzhou 730000 China 

出 版 物:《Chinese Science Bulletin》 (中国科学通报)

年 卷 期:2010年第55卷第8期

页      面:701-704页

核心收录:

学科分类:0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 080203[工学-机械设计及理论] 0802[工学-机械工程] 

基  金:supported by the National Natural Science Foundation of China (Grant Nos.20973085 and 10831001) Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant No.20090211110006) 

主  题:DNA序列 图形表示 相似性 四维 β-珠蛋白基因 生物学意义 作者 编码序列 

摘      要:In this paper,we propose a new 4D graphical representation of DNA primary sequences based on the Z-curve *** advantage of our approach is that it has the similar biological significance with the Z-curve,and it does not lose any biological information of the *** geometrical centers of the 4D graphical representation of DNA sequences are used as the numerical characterizations,and the examination of similarities/dissimilarities about the coding sequences of the first exon of β-globin genes of eleven different species shows that this approach can provide satisfactory results.

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