Preliminary X-ray diffraction study on haemorrhagin AaHⅢ from snake venom of Agkistrodon acutus

作     者：龚为民 朱中良 牛立文 滕脉坤 

作者机构：Department of BiologyUniversity of Science and Technology of ChinaHefei 230026China Young Scientist Laboratory of Structure Biology University of Science and Technology of China Hefei 230026 China State Key Laboratory of BiomacromoleculesChinese Academy of SciencesBeijing 100080China 

出 版 物：《Chinese Science Bulletin》 (科学通报(英文版))

年 卷 期：1996年第41卷第21期

页      面：1824-1826页

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

基　　金：Project supported by the State Key Laboratory of Biomacromolecules  Chinese Academy of Science and State Foundation Commission of China 

主　　题：crystal haemorrhagin metalloprotcina.se snake venom. 

摘      要：Haemorrhagins,Which cause local haemorrhage or even death after injection into exper-imental animals,exist widely in many kinds of snake *** allthe haemorrhagins reported are zinc-metalloproteinases with highly conserved amino acid *** of them could degrade the proteins in matrices so that they are the im-portant targets for drugs to combat diseases such as arthritis and *** venommetalloproteinases can be divided into three classes based on their molecular