Bioactive titanium metal surfaces with antimicrobial properties prepared by anodic oxidation treatment

作     者：YUE ChongXia YANG BangCheng ZHANG XingDong 

作者机构：Engineering Research Center for BiomaterialsSichuan UniversityChengdu 610064China National Engineering Research Center in BiomaterialsChengdu 610064China 

出 版 物：《Science China(Technological Sciences)》 (中国科学（技术科学英文版）)

年 卷 期：2009年第52卷第8期

页      面：2269-2274页

核心收录：

学科分类：080503[工学-材料加工工程] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：Supported by the National Natural Science Foundation of China (Grant Nos. 50672062 and 30870615) Key Programs for Science and Technology Development of Sichuan Province, China (Grant No. 2008SZ0104) Sichuan Youth Science & Technology Foundation, China (Grant No. 09ZQ026-033) 

主　　题：titanium anodic oxidation bioactivity antimicrobial property 

摘      要：In order to endow titanium metals with bioactivity and antimicrobial properties, titanium plates were subjected to anodic oxidation treatment in NaCl solutions in this study. The treated titanium metals could induce apatite formation in the fast calcification solution, and osteoblasts on the treated titanium surfaces proliferated well as those on the untreated titanium metal surfaces. The treated metals could inhibit S. aureus growth in the microbial culture experiments. It was assumed that Ti-OH groups and Ti-Cl groups formed on the treated titanium surface were responsible for the bioactivity and antimicrobial properties of the metals. The anodic oxidation treatment was an effective way to prepare bioactive titanium surfaces with antimicrobial properties.