The CARSO (Computer Aided Response Surface Optimization) Procedure in Optimization Studies

作     者：Mauro Fernandi Massimo Baroni Matteo Bazzurri Paolo Benedetti Danilo Chiocchini Diego Decastri Cynthia Ebert Lucia Gardossi Giuseppe Marco Randazzo Sergio Clementi 

作者机构：Flint Group Cinisello Balsamo Milano Italy Biology Biotechnology and Chemistry Department Section Chemistry University of Perugia Perugia Italy M.I.A. Multivariate Infometric Analysis Srl Perugia Italy Department of Chemistry and Pharmaceutical Sciences University of Trieste Trieste Italy 

出 版 物：《Applied Mathematics》 (应用数学（英文）)

年 卷 期：2015年第6卷第11期

页      面：1947-1956页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：CARSO Procedure Design Strategies Double Circulating Matrices (DCMs) Optimization 

摘      要：The paper illustrates innovative ways of using the CARSO (Computer Aided Response Surface Optimization) procedure for response surfaces analyses derived by DCM4 experimental designs in multivariate spaces. Within this method, we show a new feature for optimization studies: the results of comparing their quadratic and linear models for discussing the best way to compute the most reliable predictions of future compounds.