Measuring Radiotherapy Setup Errors in IMRT Treated Head and Neck Cancer Patients Requiring Bilateral Neck Irradiation, NCI-Egypt Experience
Measuring Radiotherapy Setup Errors in IMRT Treated Head and Neck Cancer Patients Requiring Bilateral Neck Irradiation, NCI-Egypt Experience作者机构：Radiation Oncology Department National Cancer Institute Cairo University Cairo Egypt Physics Unit Radiation Oncology Department National Cancer Institute Cairo University Cairo Egypt
出 版 物：《Journal of Cancer Therapy》 (癌症治疗（英文）)
年 卷 期：2017年第8卷第13期
页 面：1160-1168页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：IMRT CBCT Setup Errors Head and Neck
摘 要：Objective: We aim to quantify the magnitude of setup errors in intensity-modulated radiotherapy (IMRT) treated Head and Neck cancer patients and recommend appropriate PTV margin. Methods: 60 patients with head and neck cancer required bilateral neck irradiation were planned and treated by simultaneous integrated boost IMRT technique either treated radically or postoperative. Patients undergoing image-guided radiotherapy (IGRT) each with once weekly scheduled cone beam computed tomography (CBCT). The 3D displacements, systematic and random errors were calculated. The appropriate PTV expansion was determined using Van Herk’s formula. Results: Mean 3D displacement was 0.16 cm in the vertical direction, 0.14 cm in the horizontal direction and 0.16 cm in the longitudinal direction. Conclusion: Use of weekly CBCT allows the planning target volume (PTV) expansion to be reduced according to our setup. The appropriate clinical target volume (CTV)-PTV margin for our institute is 0.30 cm, 0.38 cm, and 0.33 cm in the horizontal, vertical, and longitudinal directions, respectively.
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