Serum Metabolic Profiling in a Mouse Model of Adriamycin-Induced Focal Segmental Glomerulosclerosis

作     者：Li Lyu Cai-Li Wang Zeng-Yan Li Ying-Jin Shi Yan-Hui Zhang Yan Mi Zhao Hu Lyu Li;Wang Cai-Li;Li Zeng-Yan;Shi Ying-Jin;Zhang Yan-Hui;Mi Yan;Hu Zhao

作者机构：Department of NephrologyQilu Hospital of Shandong UniversityJinanShandong 250012China Department of NephrologyThe First Affiliated Hospital of Baotou Medical CollegeBaotouInner Mongolia 014010China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2018年第131卷第22期

页      面：2743-2746页

核心收录：

学科分类：10[医学] 

基　　金：supported by grants from the National Natural Science Fund 

主　　题：Serum Metabolic Profiling Mouse Model 

摘      要：To the Editor:Focal segmental glomerulosclerosis (FSGS)is one of the leading causes of end-stage kidney disease.[1,2] However,no ideal intervention prevents FSGS progression due to the unclear physiopathological *** (ADR)-induced FSGS is a well-accepted model that mimics human ***,a common chemotherapeutic agent associated with nephrotoxicity,causes kidney damage by triggering imbalances between free oxygen radicals and antioxidant enzymes.