Retrospective study of a cohort of adult patients with hematological malignancies in a tropical area
Retrospective study of a cohort of adult patients with hematological malignancies in a tropical area作者机构：Cancer and Environment Research Unit Centre Léon-Bérard Oncoguyane Cancer Network Department of Medical Oncology Claude-Bernard-Lyon1 University Department of Medical Oncology Centre Léon-Bérard Department of Amazonian Health Hospital of Cayenne French West-Indies and Guiana University
出 版 物：《World Journal of Hematology》 (世界血液学杂志)
年 卷 期：2016年第5卷第1期
页 面：37-50页
学科分类：10[医学]
主 题：Tropical hematology Multiple myeloma Non-Hodgkin lymphomas Chronic lymphoid leukemia Adult T-cell-lymphoma-leukemia Hodgkin disease Chronic myeloid leukemia Acute leukemia Human T-lymphotropic virus 1 Human immunodeficiency virus
摘 要：AIM: To review the characteristics of hematological malignancies in tropical areas, and to focus on the specific difficulties regarding their management. METHODS: This is a retrospective narrative review of cases of patients with hematological malignancies. All medical files of patients with malignant disease whose treatment was coordinated by the HematoOncology service of the Cayenne Hospital in French Guiana between the 1st of January 2010 and the 31 st of December 2012 were reviewed. Clinical data were extracted from the medical files and included: Demographic data, comorbidities, serological status for human immunodeficiency virus, human T-lymphotropic virus 1(HTLV1), hepatitis B virus and hepatitis C virusinfections, cytology and pathology diagnoses, disease extension, treatment, organization of disease management, and follow-up. The subgroup of patients with hematological malignancies and virus-related malignancies were reviewed. Cases involving patients with Kaposi sarcoma, and information on solid tumor occurrence in virus-infected patients in the whole patient population were included. Since the data were rendered anonymous, no informed consent was obtained from the patients for this retrospective analysis. Data were compiled using EXCEL® software, and the data presentation is descriptive only. The references search was guided by the nature of the data and discussion. RESULTS: In total, the clinical files of 594 patients(pts) were reviewed. Hematological malignancies were observed in 87 patients, and Kaposi sarcoma in 2 patients. In total, 70 patients had a viral infection, and 34 of these also had hematological malignancies. The hematological diagnoses were: Multiple myeloma in 27 pts, lymphoma(L) in 43 pts, myeloproliferative disorders in 17 pts and Kaposi sarcoma in two patients. The spectrum of non-Hodgkin lymphomas(NHL) was: Burkitt L(1 pt), follicular L(5 pts), chronic lymphocytic leukemia(5 pts), high-grade NHL(9 pts), mucosa-associated lymphoid
维普期刊数据库