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Risk assessment instruments for screening bone mineral density in a Mediterranean population

Risk assessment instruments for screening bone mineral density in a Mediterranean population

作     者:Sotirios Christodoulou Georgios I Drosos Athanasios Ververidis Antonios Galanos George Anastassopoulos Konstantinos Kazakos 

作者机构:Department of Orthopaedic Surgery Democritus University of Thrace University General Hospital of Alexandroupolis Laboratory for Research of the Musculoskeletal System University of Athens KAT Hospital Medical Informatics Laboratory Medical School Democritus University of Thrace 

出 版 物:《World Journal of Orthopedics》 (世界骨科杂志(英文版))

年 卷 期:2016年第7卷第9期

页      面:577-583页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Osteoporosis Bone mineral density Risk assessment Dual X-ray absorptiometry Osteopenia 

摘      要:AIM To evaluate the power of six osteoporosis-screening instruments in women in a Mediterranean *** Data concerning several osteoporosis risk factors were prospectively collected from 1000 postmenopausal women aged 42-87 years who underwent dual-energy X-ray absorptiometry(DEXA) screening. Six osteoporosis risk factor screening tools were applied to this sample to evaluate their performance and choose the most appropriate tool for the study *** The most important screening tool for osteoporosis status was the Simple Calculated Osteoporosis Risk Estimation, which had an area under the curve(AUC)of 0.678, a sensitivity of 72%, and a specificity of 72%, with a cut-off point of 20.75. The most important screening tool for osteoporosis risk was the Osteoporosis Self-assessment Tool, which had an AUC of 0.643, a sensitivity of 77%, and a specificity of 46%,with a cut-off point *** Some commonly used clinical risk instruments demonstrate high sensitivity for distinguishing individuals with DEXA-ascertained osteoporosis or reduced bone mineral density.

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