Using airbrushes to pattern reagents for microarrays and paper-fluidic devices

作     者：Christopher L.Cassano Teodor Z.Georgiev Z Hugh Fan 

作者机构：Interdisciplinary Microsystems GroupDepartment of Mechanical and Aerospace EngineeringUniversity of FloridaP.O.Box 116250GainesvilleFL 32611USA J.Crayton Pruitt Family Department of Biomedical EngineeringUniversity of FloridaP.O.Box 116131GainesvilleFlorida 32611USA Department of ChemistryUniversity of FloridaP.O.Box 117200GainesvilleFL 32611USA Sandia National LaboratoryP.O.Box 5800AlbuquerqueNM 87185USA 

出 版 物：《Microsystems & Nanoengineering》 (微系统与纳米工程（英文）)

年 卷 期：2017年第3卷第1期

页      面：45-51页

核心收录：

学科分类：080903[工学-微电子学与固体电子学] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：This work was supported in part by the National Science Foundation(OISE-0968313 and DBI-1353423) via the Partnerships for International Research and Education(PIRE)program and the Instrument Development for Biological Research(IDBR)program,and by the Florida Department of Health(Grant No.7ZK22) James and Esther King Biomedical Research Program(Grant No.7JK07) 

主　　题：airbrush paper-fluidics fabrication microarrays lateral flow assays chemiluminescence 

摘      要：We report using an airbrush to pattern a number of reagents,including small molecules,proteins,DNA,and conductive microparticles,onto a variety of mechanical substrates such as paper and *** is more economical and easier to perform than many other patterning methods available(for example,inkjet printing).In this work,we investigated the controllable parameters that affect patterned line width and studied their mechanisms of action,and we provide examples of possible *** airbrushing approach allowed us to pattern lines and dot arrays from hundreds ofμm to tens of mm with length scales comparable to those of other patterning *** applications,enzymatic assays and DNA hybridization,were chosen to demonstrate the compatibility of the method with *** airbrushing method holds promise in making paper-based platforms less expensive and more accessible.