Subclinical cardiovascular disease in type 2 diabetes mellitus: To screen or not to screen
Subclinical cardiovascular disease in type 2 diabetes mellitus: To screen or not to screen作者机构:Department of Endocrinology and NutritionHospital del Mar Passeig Marítim 25-29 08003 Barcelona Spain Institut Municipal d'Investigacions Mèdiques Passeig Marítim 25-29 08003 Barcelona Spain Departament de Medicina Universitat Autònoma de Barcelona 08193 Cerdanyola (NOT Sarda?ola) del Vallés Barcelona Spain
出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期:2014年第2卷第9期
页 面:415-421页
核心收录:
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:Cardiovascular disease Type 2 diabetes mellitus Cardiovascular risk
摘 要:The prevalence of type 2 diabetes mellitus(T2DM) has risen in recent decades, and cardiovascular disease remains the leading cause of death in this population. Several clinical trials have demonstrated the benefit of tight control of risk factors on the incidence and mortality of cardiovascular disease. However, in clinical practice, few patients achieve the therapeutic goals. The current diagnostic procedures for subclinical cardiovascular disease in T2 DM patients have not been shown to improve prognosis or mortality, probably because they do not categorize cardiovascular risk. Thus, clinical practice guidelines do not systematically recommend screening for subclinical atherosclerosis in these patients, although it is known that patients with extracoronary atherosclerosis, microangiopathy and poorlycontrolled cardiovascular risk factors are at high risk for cardiovascular disease. Improvements in the reliability of diagnostic tests, with fewer side effects and better cost efficiency, may better help to stratify cardiovascular risk in this group of patients, and further evaluation on this topic should be considered.