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Total knee arthroplasty in patients with Paget's disease of bone: A systematic review

Total knee arthroplasty in patients with Paget's disease of bone: A systematic review

作     者:Ravi Popat Konstantinos Tsitskaris Steven Millington Sebastian Dawson-Bowling Sammy A Hanna 

作者机构:Department of Trauma and Orthopaedic Surgery the Hillingdon Hospitals NHS Foundation Trust Department of Trauma and Orthopaedic Surgery Barts Health NHS Trust 

出 版 物:《World Journal of Orthopedics》 (世界骨科杂志(英文版))

年 卷 期:2018年第9卷第10期

页      面:229-234页

学科分类:0403[教育学-体育学] 1002[医学-临床医学] 10[医学] 

主  题:Total knee arthroplasty Paget’s disease of bone Revision Loosening Paget’s disease 

摘      要:AIM To determine the functional outcomes, complications and revision rates following total knee arthroplasty(TKA) in patients with Paget s disease of bone(PDB). METHODS A systematic review of the literature was performed. Four studies with a total of 54 TKAs were included for analysis. Functional outcomes, pain scores, complications and revision rates were assessed. The mean age was 72.0 years and the mean follow-up was 7.5 years.RESULTS All studies reported significant improvement in knee function and pain scores following TKA. There were 2 cases of aseptic loosening, with one patient requiring revision of the femoral component 10 years after the index procedure. Malalignment, bone loss, soft tissue contractures were the most commonly reported intraoperative challenges. There were five cases(9%) that were complicated by intra-operative patellar tendon avulsion.CONCLUSION The findings support the use of TKA in patients with PDB. The post-operative functional outcomes are largely similar to other patients, however there are specific perioperative challenges that have been highlighted, in particular the high risk for patellar tendon avulsion.

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