Case series on multimodal endoscopic therapy for gastric antral vascular ectasia, a tertiary center experience

作     者：Tasnia Matin Mohammed Naseemuddin Mohamed Shoreibah Peng Li Kondal Kyanam Kabir Baig Charles Mel Wilcox Shajan Peter 

作者机构：Internal Medicine UAB Hospital Division of Gastroenterology University of Alabama School of Medicine Department of Gastroenterology Emory Division of Gastroenterology Uni-versity of Alabama at Birmingham School of Public Health University of Alabama at Birmingham 

出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)

年 卷 期：2018年第10卷第1期

页      面：30-36页

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES [UL1TR001417] Funding Source: NIH RePORTER NCATS NIH HHS [UL1 TR001417] Funding Source: Medline 

主　　题：Gastric antral vascular ectasia Upper GI bleed Radiofrequency ablation Endoscopic band ligation Argon plasma coagulation 

摘      要：AIM To study and describe patients who underwent treatment for gastric antral vascular ectasia(GAVE) with different endoscopic treatment *** We reviewed patients with GAVE who underwent treatment at University of Alabama at Birmingham between March 1, 2012 and December 31, 2016. Included patients had an endoscopic diagnosis of GAVE with associated upper gastrointestinal bleeding or iron deficiency *** Seven out of 15 patients had classic watermelon description for GAVE, 1/15 with diffuse/honeycomb pattern and 6/15 with nodular GAVE per EGD description. Seven out of 15 patients required multimodal treatment. Four out of six of patients with endoscopically nodular GAVE required multimodal therapy. Overall, mean pre-and post-treatment hemoglobin(Hb) values were 8.2 ± 0.8 g/dL and 9.7 ± 1.6 g/dL, respectively(P ≤ 0.05). Mean number of packed red blood cells transfusions before and after treatment was 3.8 ± 4.3 and 1.2 ± 1.7(P ≤ 0.05), *** Patients with nodular variant GAVE required multimodal approach more frequently than non-nodular variants. Patients responded well to multimodal therapy and saw decrease in transfusion rates and increase in Hb concentrations. Our findings suggest a multimodal approach may be beneficial in nodular variant GAVE.