The Study of the Graft Hemodynamics with Different Instant Patency in Coronary Artery Bypassing Grafting

作     者：Zhou Zhao Boyan Mao Youjun Liu Haisheng Yang Yu Chen 

作者机构：Cardiac Surgery DepartmentPeking University People’s Hospital.11th.Ave.XizhimenBeijingChina. College of Life Science and Bio-engineeringBeijing University of Technology.No.100 PingleyuanChaoyang DistrictBeijingChina. 

出 版 物：《Computer Modeling in Engineering & Sciences》 (工程与科学中的计算机建模（英文）)

年 卷 期：2018年第116卷第8期

页      面：229-245页

核心收录：

学科分类：080802[工学-电力系统及其自动化] 0808[工学-电气工程] 08[工学] 

基　　金：This work is supported by National Natural Science Foundation of China(11832003 11772016 11472022 11702008) 

主　　题：Coronary artery bypass grafting instant patency graft flow hemodynamics multi-scale model 

摘      要：In coronary artery bypass grafting(CABG),graft’s poor instant patency may lead to an abnormal hemodynamic environment in anastomosis,which could further cause graft failure after the *** paper investigates the graft hemodynamics with different instant patency,and explores its effect on graft postoperative *** CABG 0D/3D coupling multi-scale models which used left internal mammary artery(LIMA)and saphenous vein(SVG)as grafts were *** types of grafts were examined in the models,including normal grafts,grafts with competitive flow and grafts with anastomotic *** results indicated that comparing with SVG grafts,there was a greater difference between normal LIMA graft and non-patent LIMA ***,the backflow occurred even in LIMA systolic *** wall shear stress(WSS)in the graft of the competitive flow LIMA model had an appreciable decrease comparing with the normal *** addition,the WSS in the stenosis region of the anastomotic stenosis LIMA model was much higher than its adjacent *** contrast,the WSS distributions in the SVG models were much smoother than in the LIMA *** oscillatory shear index(OSI),there was little difference between normal LIMA and *** when the graft had competitive flow or anastomotic stenosis,much higher OSI occurred in some regions in LIMA than *** are significant differences in hemodynamics between normal grafts and non-patent grafts both in LIMA and *** hemodynamic environment in a normal LIMA is better than that in a normal ***,in the situation of the two types of non-patent grafts,the hemodynamics of SVG is better than LIMA.