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Surgical strategy for huge and advanced hepatocellular carcinoma in Hong Kong

Surgical strategy for huge and advanced hepatocellular carcinoma in Hong Kong

作     者:Kenneth S.H.Chok 

作者机构:Division of Hepatobiliary and Pancreatic Surgery and Liver TransplantationDepartment of SurgeryThe University of Hong KongHong KongChina 

出 版 物:《Hepatoma Research》 (肝癌研究(英文版))

年 卷 期:2017年第3卷第9期

页      面:189-195页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Associating liver partition and portal vein ligation staged hepatectomy hepatocellular carcinoma liver resection vascular resection and reconstruction radiofrequency ablation 

摘      要:In Hong Kong, surgical resection is the core curative treatment for huge and advanced hepatocellular carcinoma (HCC). For tumors measuring 10 cm or above, major hepatectomy is usually required, but a future liver remnant not large enough will preclude the operation. Hypertrophy of future liver remnant is a way to render more patients operable, and measures include portal vein embolization and associating liver partition and portal vein ligation for staged hepatectomy. For HCC that has invaded a major vessel, en bloc resection with immediate vessel reconstruction is necessary if thrombectomy would not suffice. In case of bilobar involvement, radiofrequency ablation is a useful adjuctive therapy. In the treatment of extrahepatic metastasis, metastasectomy offers a cure to properly selected patients.

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