The Effect of Paroxetine on Depressive Symptom with Somatic Disease and Change of Platelet 5-HT Concentration
The Effect of Paroxetine on Depressive Symptom with Somatic Disease and Change of Platelet 5-HT Concentration作者机构:DepartmentofNeurologyTongjiHospitalTongjiMedicalCollegeHuazhongUniversityofScienceandTechnology DepartmentofInternalMedicineTongjiHospitalTongjiMedicalCollegeHuazhongUniversityofScienceandTechnology
出 版 物:《Journal of Huazhong University of Science and Technology(Medical Sciences)》 (华中科技大学学报(医学英德文版))
年 卷 期:2003年第23卷第1期
页 面:29-31页
核心收录:
学科分类:1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学]
主 题:paroxetine depressive symptom 5-HT
摘 要:To study the effect of paroxetine on depressive symptom accompanying somatic disease and the value of platelet 5-HT concentration in the diagnosis of depression, 30 patients with depressive symptom were treated with paroxetine. All patients were evaluated on Zung and HAMD scale and assayed of platelet 5-HT concentration before and after treatment. It was found that patients had a lower level of platelet 5-HT concentration than healthy people (P0.05). It was suggested that paroxetine was a good antidepressant and platelet 5-HT concentration was useful in the screening of depression.