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Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance

Immunohistochemical detection of ras p21 expression in pancreatic adenocarcinoma and its clinicopathological significance

作     者:胡育新 许国铭 

作者机构:Department of GastroenterologyChanghai HospitalSecond Military Medical UniversityShanghai 200433 

出 版 物:《Journal of Medical Colleges of PLA(China)》 (中国人民解放军军医大学学报(英文版))

年 卷 期:1993年第8卷第4期

页      面:360-362页

学科分类:10[医学] 

主  题:pancreatic neoplasms oncogenes immunohistochemistry antibodies,monoclonal pathology human 

摘      要:By using anti-ras p21 mouse monoclonal antibody(McAb),SCI-oncogema 1,the au-thors examined immunohistochemical staining in pancreatic *** percentage ofpositive staining was 55.8%(24/43)and was related to either histopathological grade or *** statistical analysis of the correlation between the positive staining of anti-ras p21and patient prognosis with Klaplan-Meier curve and Log-rant test,the positive staining casesshowed comparatively better prognosis than the negative ones,suggesting that ras p21 expres-sion may be important in the early stage of pancreatic carcinoma.

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