Advances in fabricating spherical alginate hydrogels with controlled particle designs by ionotropic gelation as encapsulation systems
Advances in fabricating spherical alginate hydrogels with controlled particle designs by ionotropic gelation as encapsulation systems作者机构:alan Lagoon Selatan Bandar Sunway Selangor 46150 Malaysia Advanced Engineering Platform Monash University Malaysia Jalan Lagoon Selatan Bandar Sunway Selangor 46150 Malaysia Oniris UMR CNRS 6144 GEPEA rue de la Geraudiere BP82225 Nantes 44322 France
出 版 物:《Particuology》 (颗粒学报(英文版))
年 卷 期:2016年第14卷第1期
页 面:44-60页
核心收录:
学科分类:08[工学] 0805[工学-材料科学与工程(可授工学、理学学位)]
基 金:Kementerian Sains, Teknologi dan Inovasi, MOSTI, (06-02-10-SF0157) Monash University Malaysia
主 题:Alginate lonotropic gelation Immobilization Encapsulation Hydrogel
摘 要:Alginate is a biopolymer that has exceptional gelling properties, which allow easy gel formation under safe and mild conditions. Consequently, it is often used to encapsulate a variety of cargos, such as cells, enzymes, and lipids, and is typically employed as a model to study hydrogel-based encapsulation sys- tems. Since the first use of alginate in the encapsulation field in the 1970s, many methods have been developed to produce alginate hydrogel particles of different sizes, structures, and morphologies. This review provides an overview of the current progress in the fabrication of alginate hydrogels with vari- ous particle designs, including a discussion of dispersion techniques to pre-template alginate particles, gelation mechanisms, considerations in selecting suitable fabrication methods, and future directions.