Risk factors distribution and cardiovascular disease prevalence in the Italian population: The CHECK study
Risk factors distribution and cardiovascular disease prevalence in the Italian population: The CHECK study作者机构：Epidemiology and Preventive Pharmacology Centre (SEFAP) University of Milano Milano Italy IRCCS Multimedica Sesto S. Giovanni Milano Italy Italian Society of General Medicine (SIMG) Firenze Italy Kingston University Kingston upon Thames UK
出 版 物：《Open Journal of Epidemiology》 (流行病学期刊（英文）)
年 卷 期：2012年第2卷第4期
页 面：90-100页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Italian Population Epidemiological Study Cardiovascular Risk Factors Prevalence of Cardiovascular Disease
摘 要：Objective: To evaluate the distribution of cardiovascular risk factors and the prevalence of cardiovascular disease in a sample of the Italian population. Methods: CHECK (Cholesterol and Health: Education, Control and Knowledge) is a cross-sectional observational study in a randomised sample of the Italian adult population aged 40 - 79 years, in the setting of general practice. Results: 5846 subjects (50.3% male) were included in the analysis. The mean age [±SD] of the observed cohort was 57.8 (±10.3) years. One out of five subjects smoked cigarettes and almost 80% didn’t engage in regular leisure-time physical activity. The mean blood pressure was 132.0 [±14.7]/81.2 [±7.9] mmHg. The total and LDL-cholesterol levels were respectively 205.3 [±35.9] mg/dL and 124.9 [±29.9] mg/dL. The mean glucose concentration was 98.3 [±28.2] mg/dL. The prevalence rate of hypertension, hypercholesterolemia, and type 2 diabetes were respectively 51.8%, 55.6%, and 13.0%. 8.9% of the observed subjects had a history of cardiovascular events, while in the primary prevention group the 10-year-risk of coronary heart disease (Framingham algorithm) was 10.1% [±8.3%] and of cardiovascular disease (CUORE algorithm) was 5.2% [±5.9%]. Conclusion: The CHECK study provides a detailed description of a randomised sample of the Italian population, contributing to evaluate the prevalence of cardiovascular risk factors and the main cardiovascular disease in Italy and to provide a baseline to set priorities and objectives for future intervention of health policy.
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