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Smoking behavior of HIV-infected patients

Smoking behavior of HIV-infected patients

作     者:Till Neumann Nico Reinsch Stefan Esser Peter Krings Thomas Konorza Tanja Woiwoid Michael Miller Norbert Brockmeyer Raimund Erbel 

作者机构:不详 

出 版 物:《Health》 (健康(英文))

年 卷 期:2010年第2卷第8期

页      面:913-918页

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Human Immunodeficiency Virus Atherosclerosis Smoking Tobacco Consumption 

摘      要:Recent reports describe an increased rate of cardiovascular events in smoking HIV-infected subjects. However, a lot is still unknown about smoking in this patient population. The purpose of the study was to analyze smoking behavior in HIV-infected subjects as a risk factor of coro-nary atherosclerosis and determine its effect on the probability of coronary events. We analyzed the cardiovascular risk factors of 294 HIV-infected adults (age: 42.1 ? 10.1 years;77% males). An elevated tobacco abuse was observed in 63.6% of the HIV-infected patients. Tobacco use was much more common in HIV-infected males than in females (67.8% vs. 49.2%;p 0.2). Analysing the way of infection and the status of smoking, patients with HIV-infection acquired by heterosexual contact exhibited sig-nificantly lower rates of smoking compared with patients with HIV-infection acquired by MSM (man having sex with man) or by intravenous drug abuse (52.7% vs. 67.4%/82.1%, p 0.01). The effect of smoking on the 10yrs. probability of coronary events determined by Framingham- equation was superior compared with all other classic cardiovascular risk factors. HIV-infected patients exhibited an increased tobacco use. Knowledge about smoking behavior in this pa-tient population is essential to evaluate the risk of cardiovascular events and to implicate prevention strategies for HIV-infected subjects.

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