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Acute headache in general neurology of China: Cause changes and predictors of short-term outcome

Acute headache in general neurology of China: Cause changes and predictors of short-term outcome

作     者:Guangsheng Wang Yeting Zhou Xiaodong Chen Hongjian Wang Tonghui Yang Chunhong Chang Yuanwei Wang Hanpei Gu Daoming Tong 

作者机构:Department of Medical Affairs Shuyang People’s Hospital Shuyang China Departments of Neurology Shuyang People’s Hospital Shuyang China Medical Evaluation Unit Shuyang People’s Hospital Shuyang China 

出 版 物:《World Journal of Neuroscience》 (神经科学国际期刊(英文))

年 卷 期:2012年第2卷第2期

页      面:98-102页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Acute Headache Causes Cerebrovescular Events Subarachnoid Hemorrhage Outcome 

摘      要:Background: Although patients with acute headache frequently present in emergency department, the causes and predictors of short-term outcome in patients with acute headache in general neurology have not been adequately investigated. Methods: We prospectively reviewed the medical records of 130 hospitalized acute headache pa-tients in general neurology of China. Their initial CT scan was assessed, as was their lumbar puncture (LP) examination if performed. Results: The main cause of acute headache was acute secondary headache (80.8%), which was mainly attributable to acute cerebrovascular events (72.4%) followed by intracranial infection (19.0%). Among the 10.8% of patients who died during hospitalization most (85.7%) had subarachnoid hemorrhage (SAH). Significant predictors of survival were severe headache versus thunderclap headache, meningismus, de-layed loss of consciousness, and hypertension (all p 0.05). Multiple logistic regression analyses showed significant differences in severe headache or thunderclap headache (OR, 0.255;95%CI, 0.066 - 0.990;p = 0.048) and delayed loss of consciousness (OR, 0.060;95%CI, 0.016 - 0.224, p = 0.000) between patients who died and those who survived. Conclusions: The main underlying cause of hospitalized acute headache was acute cerebrovascular events. Severe headache and delayed loss of consciousness are predictors for poor outcome of acute headache.

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