Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review
Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review作者机构:Department of Orthopaedics Mayo Clinic Rochester USA. Orthopaedic Research of Virginia Richmond USA
出 版 物:《Open Journal of Orthopedics》 (矫形学期刊(英文))
年 卷 期:2013年第3卷第1期
页 面:23-28页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:Thermal Shrinkage Thermoplasty Heat-Shock AT2 Radiofrequency Collagen Denaturation Tendinosis Wound Healing Response Tendinopathy Microtenotomy Antinociceptive
摘 要:Tendinosis is now understood as the result of a failed tendon healing process regardless of where it occurs in the body. Current noninvasive therapeutic alternatives are anti-inflammatory in nature and outcomes are unpredictable at best. The benefit of invasive alternatives resides in the induction of the healing response as demonstrated in pre-clinical and clinical studies in cardiology and orthopaedics. A new technology that employs noninvasivemonopolar capacitive-coupled radiofrequency (mcRF), has demonstrated the ability to raise temperatures in tendons and ligaments upwards of 50°C, the temperature threshold for collagen modulation and recruitment of macrophages, fibroblasts and Heat Shock Protein factors—without damaging the overlying structures—resulting in activation of the Wound Healing Response (WHR).