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Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review

Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review

作     者:Terry L. Whipple Scott P. Steinmann 

作者机构:Department of Orthopaedics Mayo Clinic Rochester USA. Orthopaedic Research of Virginia Richmond USA 

出 版 物:《Open Journal of Orthopedics》 (矫形学期刊(英文))

年 卷 期:2013年第3卷第1期

页      面:23-28页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Thermal Shrinkage Thermoplasty Heat-Shock AT2 Radiofrequency Collagen Denaturation Tendinosis Wound Healing Response Tendinopathy Microtenotomy Antinociceptive 

摘      要:Tendinosis is now understood as the result of a failed tendon healing process regardless of where it occurs in the body. Current noninvasive therapeutic alternatives are anti-inflammatory in nature and outcomes are unpredictable at best. The benefit of invasive alternatives resides in the induction of the healing response as demonstrated in pre-clinical and clinical studies in cardiology and orthopaedics. A new technology that employs noninvasivemonopolar capacitive-coupled radiofrequency (mcRF), has demonstrated the ability to raise temperatures in tendons and ligaments upwards of 50°C, the temperature threshold for collagen modulation and recruitment of macrophages, fibroblasts and Heat Shock Protein factors—without damaging the overlying structures—resulting in activation of the Wound Healing Response (WHR).

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