STUDIES ON ANALOGS OF Qinghaosu——SOME ACIDIC DEGRADATIONS OF Qinghaosu

作     者：李英 虞佩琳 陈一心 张景丽 吴毓林 LI YING YU PEILIN CHEN YIXIN(Shanghai Institute of Materia Medica, Academia Sinica)ZHANG JINGLI WU YULIN(Shanghai Institute of Organic Chemistry, Academia Sinica)

作者机构：Shanghai Institute of Materia Medica Academia Sinica Shanghai Institute of Organic Chemistry Academia Sinica Shanghai Institute of Organic Chemistry Academia Sinicainghaosu 1 isolated from Artemisia annua L. has attracted great interest in recent years owing to its unique chemical structure and potent antimalarial activity especially against chloroquine-resistant faleiprum malaria. A series of studies have been carried out on its reactions total synthesis and analogs.For preparation of more Qing- 

出 版 物：《Chinese Science Bulletin》 (科学通报(英文版))

年 卷 期：1986年第31卷第15期

页      面：1038-1041页

学科分类：07[理学] 0703[理学-化学] 

主　　题：analogs potent Artemisia aldehyde afford desirable substituent hexane methanol membered 

摘      要：Qinghaosu 1 isolated from Artemisia annua L. has attracted great interest in recent years owing to its unique chemical structure and potent antimalarial activity, especially against chloroquine-resistant faleiprum malaria. A series of studies have been carried out on its reactions, total synthesis and *** preparation of more Qing-