EFFECTS OF METAL IONS ON THE CONFORMATIONAL CHANGES OF DNA

作     者：G. Q. Liu Y. Y. Meng S.H. Liu Y.H. Hu 

作者机构：Laser Life Science Institute South China Normal University Guangzhou 510631China Department of Medical Oncology Cancer Center Sun Yat-sen University of Medical Sciences Guangzhou 510060 China 

出 版 物：《Acta Metallurgica Sinica(English Letters)》 (金属学报（英文版）)

年 卷 期：2005年第18卷第5期

页      面：659-663页

核心收录：

学科分类：08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

基　　金：This work was supported by Guangdong Provincial Natural Science Foundation of China(No.021093) Guangdong Keystone Science and Technology Foundation(No.2KM04502S) Guangdong Universities Natural Science Research Foundation(No.200018) 

主　　题：DNA conformation transition mechanism condensation 

摘      要：DNA takes on multi-different conformations such as A-, B-, C-, D- and Z-form. These conformations can transit to one another when DNA deposited in some metal ions solutions or when changing the concentrations of the same metal ions. Here, several major conformational transitions of DNA induced by metal ions under different environment were introduced and the mechanism of the interaction of metal ions with DNA was discuss in detail.