INTRASPINAL CONNECTIONS OF DORSAL COLUMN POSTSYNAPTIC NEURONS IN THE CAT——A PHYSIOLOGICAL ANALYSIS

作     者：吕国蔚,GARY J.BENNETT,NOZOMU NISHIKAWA,MARVIN J.HOFFERT,RONALD DUBNER 

作者机构：Department of Neurophysiology Beijing Second Medical College China Neurobiology and Anesthesiology Branch National Institute of Dental Research National Institutes of Health USA Neurobiology and Anesthesiology Branch National Institute of Dental Research National Institutes of Health USA Department of Anesthesiology Shiga University of Medical Seience Shiga Japan Neurobiology and Anesthesiology Branch National Institute of Dental Research National Institutes of Health USA Department of Neurology Univeraity of Wisenonsin Medieal School Madison Wisconsin 53792 U.S.A Neurobiology and Anesthesiology Branch National Institute of Dental Research National Institutes of Health USA 

出 版 物：《Science China Chemistry》 (中国科学:化学(英文版))

年 卷 期：1985年第28卷第9期

页      面：972-978页

核心收录：

基　　金：This work was supported by the International Research Fund of the Fogarty International Center  National Institute of Health  Bethesda  Maryland 20205  U.S.A 

主　　题：A PHYSIOLOGICAL ANALYSIS 

摘      要：Dorsal column postsynaptic (DCPS) neurons in the dorsal horn of the spinal cord have been identified by antidromic stimulation and intracellularly recorded in anesthetized cats. In about one-half of the cells, the antidromic stimulus evokes only an antidromic potential. This potential sometimes has an atypical shape due to penetration-induced depolarization. Atypieal potentials arc converted into typical antidromic spike potentials after intracellular injection of hyperpolarizing current. In the other one-half, the antidromic potentials are followed by postsynaptic activity. Intracellular analysis indicates that this postsynaptic activity is generated largely by activation of the intraspinal collaterals of A-beta primary afferents that are ascending the dorsal columns. Part of this postsynaptic activity has been produced monosynaptically. Polysynaptic responses are also evident; these are thought to be initiated by A-beta axons, desending axons from neurons in the dorsal column nuclei, or the local coll