Management of Adult Growth Hormone Deficiency at Peking Union Medical College Hospital:A Survey among Physicians

作     者：Hong-bo Yang Meng-qi Zhang Hui Pan Hui-juan Zhu 

作者机构：Department of EndocrinologyPeking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical College Department of PediatricsPeking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical College 

出 版 物：《Chinese Medical Sciences Journal》 (中国医学科学杂志（英文版）)

年 卷 期：2016年第31卷第3期

页      面：168-172页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：Supported by National Natural Science Foundation of China(81400774) PUMC Youth Fund(33320140164 and 3332016128) 

主　　题：重组人生长激素 教学医院 缺乏症 管理 北京 医师 内科 中国医学科学院 

摘      要：Objective To evaluate physicians attitude and knowledge about the management of adult growth hormone deficiency(AGHD) at Peking Union Medical College Hospital and impact factors associated with better decision-making.Methods A 21-question anonymous survey was distributed and collected at Peking Union Medical College Hospital,a major teaching hospital in Chinese Academy of Medical Sciences.Data of physicians educational background,clinical training,patient workload per year and continuing medical education in AGHD were collected.Factors associated with appropriate answers were further analyzed by multivariate regression models.Results One hundred and eighteen internal medicine residents,endocrine fellows,attending physicians and visiting physicians responded to the survey.Among them,44.9% thought that AGHD patients should accept recombinant human growth hormone replacement therapy.Moreover,56.8% selected insulin tolerance test and growth hormone-releasing hormone-arginine test for the diagnosis of AGHD.Logistic regression analysis of physician demographic data,educational background,and work experience found no consistent independent factors associated with better decision-making,other than continued medical education,that were associated with treatment choice.Conclusions The physicians reported management of AGHD in this major academic healthcare center in Beijing was inconsistent with current evidence.High quality continued medical education is required to improve Chinese physician management of AGHD.