Effect of beta-tricalcium phosphate/poly-1-lactide composites on radial bone defects of rabbit
Effect of beta-tricalcium phosphate/poly-l-lactide composites on radial bone defects of rabbit作者机构：Medical Board of Graduate School of Suzhou University Orthopedic Surgery of 6th People-s Hospital affiliated to Shanghai Jiaotong University Orthopaedic DepartmentFirst Hospital of Lanzhou University Materials Science and Engineering Institute of Light Alloy Precision Forming National Engineering Research Center of Shanghai Jiaotong University
出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)
年 卷 期：2013年第6卷第9期
页 面：753-756页
核心收录：
学科分类：1002[医学-临床医学] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学]
基 金：suppoted by the National Natural Science Foundution of China(NSFC)(No.81271988) Shanghat Sereure and Technology Commissiop project No.11DJ1400304.No.12441903102) the crseatobgrant of Matertals Science and Engineering College of Shanghal Jraolong University and the research grant of the 6th Peoples Hospital affiliated to Shanghai Jiaolong University
主 题：β-TCP/PLLA Large segment of simulated-bioactive bone substitute Bone defect
摘 要：Objective:To explore the effect ofβ-TCP/PLLA scaffold in repairing rabbit radial lone ***:Thirty New Zealand rabbits were divided intoβ-TCP/PLLA group(group A),pure PLLA group(group B)and contrast group(group C)*** rabbits were sacrificed respectively after 4.8.12,24 weeks and the X-ray film was performed at the same time to evaluate the repair effect in different ***:X-ray film showed there was uneven low density bone callus development in defect region after 4 weeks in group *** defect region was filled with neonate osseous tissue completely during 12-24 weeks.X-ray score revealed that repair of bone defect results significantly better than group B and group ***:Theβ-PCP/PLLA composite is capable of repairing radial lone lone defects.β-TCP/PLLA scaffold is significant because of rapid degradation ability,good histocompatihility and osteogenic action.
维普期刊数据库