Beverage intake preference and bowel preparation laxative taste preference for colonoscopy

作     者：Adeyinka O Laiyemo Clinton Burnside Maryam A Laiyemo John Kwagyan Carla D Williams Kolapo A Idowu Hassan Ashktorab Angesom Kibreab Victor F Scott Andrew K Sanderson 

作者机构：Department of MedicineHoward University College of Medicine Howard University Cancer Center Department of Biological SciencesCollege of Arts and Sciences Howard University Georgetown-Howard Universities Center for Clinical and Translations Science 

出 版 物：《World Journal of Gastrointestinal Pharmacology and Therapeutics》 (世界胃肠药理与治疗学杂志（英文版）（电子版）)

年 卷 期：2015年第6卷第3期

页      面：84-88页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by In part,the Bridge Funds and Pilot Study Awards Program of Howard University,No.U400043 by grant awards from the National Center for Advancing Translational Science,Nos.KL2TR000102-04 and UL1RT000101 from the National Institute for Diabetes,Digestive Diseases and Kidney,No.R21DK100875 National Institutes of Health(to Dr.Laiyemo AO) 

主　　题：Bowel preparation Laxatives Colonoscopy Taste tests Colon cancer Screening 

摘      要：AIM: To examine whether non-alcoholic beverage intake preferences can guide polyethylene glycol(PEG)-based bowel laxative preparation selection for ***: We conducted eight public taste test sessions using commercially procured(A) unflavored PEG,(B) citrus flavored PEG and(C) PEG with ascorbate(Moviprep). We collected characteristics of volunteers including their beverage intake preferences. The volunteers tasted the laxatives in randomly assigned orders and ranked the laxatives as 1st, 2nd, and 3rd based on their taste preferences. Our primary outcome is the number of 1st place rankings for each preparation. RESULTS: A total of 777 volunteers completed the study. Unflavored PEG was ranked as 1st by 70(9.0%), flavored PEG by 534(68.7%) and PEG with ascorbate by173(22.3%) volunteers. Demographic, lifestyle characteristics and beverage intake patterns for coffee, tea, and carbonated drinks did not predict PEG-based laxative ***: Beverage intake pattern was not a useful guide for PEG-based laxative preference. It is important to develop more tolerable and affordable bowel preparation laxatives for colonoscopy. Also, patients should taste their PEG solution with and without flavoring before flavoring the entire gallon as this may give them more opportunity to pick a pattern that may be more tolerable.