Comparative proteomics reveals the response and adaptation mechanisms of white Hypsizygus marmoreus against the biological stress caused by Penicillium

作     者：Xiuqing Yang Sizhu Li Xiaohang Li Chenxiao Zhang Meijie Liu Lizhong Guo Lin Liu Hao Yu Xiuqing Yang;Sizhu Li;Xiaohang Li;Chenxiao Zhang;Meijie Liu;Lizhong Guo;Lin Liu;Hao Yu

作者机构：Shandong Provincial Key Laboratory of Applied MycologySchool of Life SciencesQingdao Agricultural UniversityQingdao 266109China 

出 版 物：《Food Science and Human Wellness》 (食品科学与人类健康（英文）)

年 卷 期：2024年第13卷第3期

页      面：1645-1661页

核心收录：

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 09[农学] 0902[农学-园艺学] 090202[农学-蔬菜学] 

基　　金：funded by the Shandong Provincial Natural Science Foundation,China (ZR2020QC005) the National Natural Science Foundation of China (32272789) the National Natural Science Foundation of China (32000041) the Shandong Edible Fungus Agricultural Technology System (SDAIT-07-02) the Shandong Provincial Key Research and Development Plan (2021ZDSYS28) the Qingdao Agricultural University Scientific Research Foundation (6631120076) 

主　　题：Hypsizygus marmoreus Penicillium Proteomics Biological stress response Adaptation 

摘      要：White Hypsizygus marmoreus is a popular edible *** mycelium is easy to be contaminated by Penicillium,which leads to a decrease in its quality and *** could compete for limited space and nutrients through rapid growth and produce a variety of harmful gases,such as benzene,aldehydes,phenols,etc.,to inhibit the growth of *** mycelium.A series of changes occurred in *** proteome after contamination when detected by the label-free tandem mass spectrometry(MS/MS)*** proteins with up-regulated expression worked together to participate in some processes,such as the non-toxic transformation of harmful gases,glutathione metabolism,histone modification,nucleotide excision repair,clearing misfolded proteins,and synthesizing glutamine,which were mainly used in response to biological *** proteins with down-regulated expression are mainly related to the processes of ribosome function,protein processing,spliceosome,carbon metabolism,glycolysis,and *** reduction in the function of these proteins affected the production of the cell components,which might be an adjustment to adapt to growth *** study further enhanced the understanding of the biological stress response and the growth restriction adaptation mechanisms in edible *** also provided a theoretical basis for protein function exploration and edible mushroom food safety research.