Shed a New Light on Spinal Cord Injury-induced Permanent Paralysis with the Brain-spine Interface

作     者：Shuang Zou Yang Zheng Xuhong Jiang Yu-Long Lan Zhong Chen Cenglin Xu 

作者机构：Xinhua Hospital of Zhejiang ProvinceThe Second Affiliated Hospital of Zhejiang Chinese Medical UniversityKey Laboratory of Neuropharmacology and Translational Medicine of Zhejiang ProvinceSchool of Pharmaceutical ScienceZhejiang Chinese Medical UniversityHangzhou310053China Department of NeurologyZhejiang Provincial Hospital of Chinese MedicineThe First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhou310060China Department of NeurosurgerySecond Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou310000China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2023年第39卷第12期

页      面：1898-1900页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by grants from the National Natural Science Foundation of China(82173796) 

主　　题：injuries stimulation thereby 

摘      要：How to deal with severe spinal cord injuries(SCI)?This question remains an everlasting challenge for *** innovative therapies such as neuromodulation,which targets the surviving tissue,have shown the potential to restore cognitive functions in patients with severe SCI after rehabilitation[1,2].These therapies might enable SCI patients to sustain active movements during rehabilitation training to enhance the reorganization of the neuronal pathways,however,the complete recovery of body movement functions was still not reached with these therapies.A characteristic feature of SCI is the impairment of neural information communication between the neurons in the spinal cord and the brain,which are responsible for regulating body ***-computer interfaces(BCIs)have been successfully applied in dealing with movement dysfunction by establishing a direct connection between brain cortical activity and electrical muscle stimulation,thereby restoring limb function in cases of paralysis[2].